Eloise Hempel is on her way to teach her first class at Harvard when she receives the devastating news that her sister and her husband have been killed in a tragic accident. Eloise leaves her life in Cambridge and moves back into her family’s century-old house in Cincinnati, pouring her own money into the house’s upkeep and her heart into raising her sister’s three children, Theodora, Josh, and Claire. Nearly twenty years later, the now-grown children seem ready to leave home, and Eloise plans to sell the house and finally start a life that’s hers alone. But when Eloise’s mother decides that they should all compete for the chance to keep the house and Claire reveals a life-changing secret, the makeshift family begins to fall apart and ultimately must decide what in life is worth fighting for.