Gifty is a sixth-year PhD candidate in neuroscience at the Stanford University School of Medicine studying reward-seeking behavior in mice and and the neural circuits of depression and addiction. Her brother, Nana, was a gifted high school athlete who died of a heroin overdose after an ankle injury left him hooked on OxyContin. Her suicidal mother is living in her bed. Gifty is determined to discover the scientific basis for the suffering she sees all around her. But even as she turns to the hard sciences to unlock the mystery of her family's loss, she finds herself hungering for her childhood faith and grappling with the evangelical church in which she was raised, whose promise of salvation remains as tantalizing as it is elusive.

Gifty, américaine d’origine ghanéenne, est une jeune chercheuse en neurologie qui consacre sa vie à ses souris de laboratoire. Mais du jour au lendemain, elle doit accueillir chez elle sa mère, très croyante, qui n’est plus que l’ombre d’elle-même et reste enfermée dans sa chambre. Au fil de souvenirs d’enfance émouvants, Gifty s’interroge sur sa passion pour la science si opposée aux croyances de sa mère et de ses ancêtres.