La Femme en Blanc est un roman policier mettant en scène Walter Hartright, qui découvre un lien entre une femme mystérieuse et sa vie à Limmeridge House. L'histoire, qui met en scène le crime et l'erreur d'identité, met en scène le complot du comte Fosco et de Sir Percival Glyde contre Laura Fairlie. Les thèmes incluent l'amour, la culture et la société.

After meeting a strange woman one night in London, Walter Hartright begins to realise that this mysterious woman is connected, in some way, to his new life at Limmeridge House and the woman he loves, Laura Fairlie. The story is told through different characters, and soon we find Walter, Marian and Laura caught up in a frightening world of crime, madness and mistaken identity. Count Fosco with Sir Percival Glyde, will do anything to get their hands on Laura’s money and think up a terrible crime that could destroy her life forever.